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Is the cardiotoxicity risk higher in female COVID-19 patients

Chloroquine, Hydroxychloroquine (less toxic quinolone-derivative of chloroquine) and remdesivir and are drugs being assessed for their potential to slow COVID-19 disease progression or improve survival 1,2. Anecdotal clinical data also suggests elevated efficacy of hydroxychloroquine treatment in combination with azithromycin for hospitalized COVID-19 patients 3,4.

Remdesivir, being a new…

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Drug Drug Interactions - A study into this effect

More drugs and many combinations of drugs are being used to treat patients than ever before, increasing the chances of reactions amongst prescribed drugs. Adverse Drug Reactions cause over 106,000 deaths annually, making ADRs the 4th leading cause of death in US, ahead of pulmonary disease, diabetes, AIDS, pneumonia and automobile deaths.

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Drug and your Genetics - A study into this effect

Pharmacogenomics is the use of genetic testing to maximize drug efficacy and avoid adverse effects based on personalized genetic information. ContraRx will offer personalized PharmacoGenomic services utilizing patients stem cell derived hepatocytes. This personalized pharmacogenomic information can play a key role in making better prescription decisions and clinical actions.
Response rates to…

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Drug Food Interactions - A study into this effect

A drug-food interaction occurs when your food and medicine interfere with one another. Interactions can happen with both prescription and over-the-counter medicines. These include antacids, vitamins, and iron pills. Not all medicines are affected by food. Some, though, are affected by what you eat or when you eat it. Taking medicine at the same time you eat…

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Drug Herbal Interactions - A study into this effect

Regulatory authorities mandate detailed metabolism & elimination studies for all Investigational New Drugs (INDs). The metabolism studies identify the enzymes that catalyze the main systemic and pre-systemic elimination pathways. Important interactions between drugs can be predicted by using a list of drugs that are inhibitors or inducers of a specific enzyme providing a framework for…

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